Preparation of Hydroxyapatite Scaffold using Luffa Cylindrica Sponge as Template

Ahmad Fadli, Prihartini Widiyanti, Deni Noviana, Agung Prabowo, Heni Ismawati

Abstract


Hydroxyapatite (HA) scaffold has been widely applied in the biomedical field especially for bone implants. The purpose of this research is to determine the influence of dispersant addition and stirring time on HA scaffold which formed using gambas sponges as a template. HA slurry was made by mixing 10 grams of HA, 12 grams of aquadest, 0,2; 0,25; 0,3 grams of Darvan 821A and 1 gram of sago. The slurry was impregnated into Luffa cylindrica sponges. The sample then dried at 110oC for 3 hours. The green bodies were burned at 600oC for 1 hour and followed by sintering at 1250oC for 1 hour. The results showed that the addition of dispersant and increasing of stirring time lead to smaller porosity and shrinkage. In addition 0,2; 0,25; and 0,3 grams dispersant, the resulting porosity in the range of 63,85-70,78%; 58,74-70,35%; and 53,42-69,66%. Shrinkage 39,43-53,71%; 27,75-50,68%; and 13,61-41,25%. Compressive strength 0,61-1,05 MPa; 2,88-3,81MPa; and 0,52-2,96 MPa. The macroporous and microporous average pore sized was 50 µm dan 5 µm.


Keywords


Hydroxyapatite; Luffa cylindrica; sponge; porous

Full Text:

PDF

References


Swain, S.K., S. Bhattacharyya., dan D. Sarkar. 2015. Fabrication of Porous Hydroxyapatite Scaffold Via Polyethylene Glycol-Polyvinyl Alcohol Hydrogel State. Materials Research Bulletin 64: 257-261.

Sopyan, I., dan J. Kaur. 2009. Preparation and Characterization of Porous Hydroxyapatite Through Polymeric Sponge Method. Ceramic International 35: 3161-3168

Doboš, P. 2012. Synthesis of Foamed Bioceramics for Potential Medical Applications. Thesis. Faculty of Chemistry. Brno University of Technology. Purkyňova.

Barbara, L., G. Hulya., S. H. Irsen., S. Milz., C. Tille., M. Schieker., H. Seitz. 2005. Hydroxyapatite Scaffolds for Bone Tissue Engineering Made by 3D Printing. Journal of Material Science: Materials in Medicine. 16: 1121-1124

Tanobe, V.O.A., T.H.D. Sydenstrickera, M. Munaro, dan S.C. Amico. 2005. A comprehensive characterization of chemically treated Brazilian sponge-gourds (Luffa cylindrica). Polymer Testing 24: 478-482.

Zampieri, A., G.T.P. Mabande, T. Selvam., W.Schwieger., A. Rudolph., R. Hermann, H. Sieber., dan P. Greil. 2006. Biotemplating of Luffa cylindrica sponges to self-supporting hierarchical zeolite macrostructures for bio-inspired structured catalytic reactors. Materials Science and Engineering C 26. 130-135.

Jamaludin A.R., S.R. Kasim., A.K. Ismail., M.Z. Abdullah., dan Z.A. Ahmad. 2015. The Effect of Sago as Binder in the Fabrication of Alumina Foam Through the Polymeric Sponge Replication Technique. Journal of the European Ceramic Society 35: 1905-1914.

Fu, Q., M.N. Rahaman., F. Dogan., dan B.S. Bal. 2008. Freeze Casting of Porous HA Scaffolds.Processing & General Microstructure. Journal of Biomedical Materials Research Part B: Applied Biomaterials: 125-135.

Kang, S.J.L. 2005. Sintering, Densification, Grain Growth & Microstructure. Elsevier Butterworth-Heinemann. Burlington. UK.

Li, S., Huang, B., Chen, Y., Gao, H., Fan, Q., Zhao, J., dan Su, W. 2013. Hydroxyapatite-coated femoral stems in primary total hip arthroplasty: a meta-analysis of randomized controlled trials. International Journal of Surgery. 11 (6): 477-482.

Zhang, M., and Ramay, H. R., 2003. Preparation of porous hydroxyapatite scaffolds by combination of the gel-casting dan polymer sponge methods. Biomaterials 24: 3293-3302.

Rahman H.A., and Guan YC. 2007. Preparation of Ceramic Foam by Simple Casting Process. International Conference on Engineering and Environment; 2007 May 10-11; Phuket, Thailand.




DOI: https://doi.org/10.23955/rkl.v15i2.15957

Refbacks



Copyright (c) 2020 Ahmad Fadli, Prihartini Widiyanti, Deni Noviana, Agung Prabowo, Heni Ismawati

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

JURNAL REKAYASA KIMIA & LINGKUNGAN

Jurusan Teknik Kimia Universitas Syiah Kuala, Jl. Tgk. Syech Abdur Rauf No.7, Kopelma Darussalam, Banda Aceh, INDONESIA

 

PRINCIPAL CONTACT

Nasrul Arahman, Prof. Dr. S.T., M.T.
Phone: +62813-6092-7917
E-mail: rkl@che.unsyiah.ac.id, nasrular@unsyiah.ac.id

 

SUPPORT CONTACT

Mirna Rahmah Lubis
E-mail: mirna@che.unsyiah.ac.id
Wahyu Rinaldi, ST, M.Sc.
E-mail: wahyu.rinaldi@che.unsyiah.ac.id

 

VISITORS